CPT Regional groups are built around a core of trained CPTers and CPT supporters that work to reduce violence both in their local regions and by supporting or serving on already-established CPT projects.

For example, CPT Cleveland originally formed to reduce violence related to drug trafficking in their neighborhood. CPT Manitoba has chosen to focus on issues relating to CPT's Colombia project and local First Nation's issues.

CPT regional groups engage in a variety of activities: nonviolent direct actions, organizing speaking tours, lobbying government officials, and serving on CPT projects. CPT regional groups can function as a spiritual support community for people doing a lot of peace organizing.

When at least ten people from a region apply to become CPT Reservists (3-year term, 2-8 weeks service per year), CPT will work with that group to plan a regional training.

The process for becoming a CPT Reservist includes first participaing in a CPT delegation, and then applying to become part of the Peacemaker Corps.